发明名称 |
USE OF SEROTONIN REUPTAKE INHIBITOR FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS. |
摘要 |
<p>The present invention refers to imidazoline indol such as 3-[2-(4,5-dihydro-1H-imidazol-2-yl)ethyl]-5-fluoro-1H-indol and the pharmaceutically acceptable salts thereof, which blocks the extracellular reuptake of the serotonin monoaminergic neurotrasnsmitter (5-hidroxytriptamine or 5-HT) in the presynaptic neuron, thus increasing the effective concentration of this neurotransmitter so as to be linked to the postsynaptic receptors 5-HT. The compounds of the invention are applied in neuro-psychiatric diseases such as depression.</p> |
申请公布号 |
MX2014011573(A) |
申请公布日期 |
2015.03.10 |
申请号 |
MX20140011573 |
申请日期 |
2014.09.25 |
申请人 |
CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL I. P. N. |
发明人 |
MARTHA SONIA MORALES RÍOS;BENJAMÍN GARCÍA VÁZQUEZ;BENJAMÍN FLORÁN GARDUÑO;MARÍA TRINIDAD SERRANO ALVA |
分类号 |
C07D209/06;A61K31/404 |
主分类号 |
C07D209/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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