发明名称 USE OF SEROTONIN REUPTAKE INHIBITOR FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS.
摘要 <p>The present invention refers to imidazoline indol such as 3-[2-(4,5-dihydro-1H-imidazol-2-yl)ethyl]-5-fluoro-1H-indol and the pharmaceutically acceptable salts thereof, which blocks the extracellular reuptake of the serotonin monoaminergic neurotrasnsmitter (5-hidroxytriptamine or 5-HT) in the presynaptic neuron, thus increasing the effective concentration of this neurotransmitter so as to be linked to the postsynaptic receptors 5-HT. The compounds of the invention are applied in neuro-psychiatric diseases such as depression.</p>
申请公布号 MX2014011573(A) 申请公布日期 2015.03.10
申请号 MX20140011573 申请日期 2014.09.25
申请人 CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL I. P. N. 发明人 MARTHA SONIA MORALES RÍOS;BENJAMÍN GARCÍA VÁZQUEZ;BENJAMÍN FLORÁN GARDUÑO;MARÍA TRINIDAD SERRANO ALVA
分类号 C07D209/06;A61K31/404 主分类号 C07D209/06
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