DIAMIDE COMPOUNDS POSSESSING MUSCARINIC ANTAGONIST ACTIVITY AND B2 ADRENERGIC RECEPTOR B2 AGONIST ACTIVITY

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to 1-(2-{[4-(4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}phenylcarbamoyl)butyl]methylcarbamoyl}ethyl)piperidin-4-yl ester of biphenyl-2-ylcarbamic acid or to its pharmaceutically acceptable salt. The invention also refers to a pharmaceutical composition based on the above compound, a method and an intermediate compound for producing the above compound.EFFECT: produced is the new heterocyclic compound effective in treating pulmonary disorders, including in chronic obstructive pulmonary disease or asthma.9 cl, 3 tbl, 170 ex