Methods for adaptive limb occlusion

摘要

Methods for adaptive cuff inflation for the purposes of occluding a limb of a subject include inflating a cuff to a pressure at or above limb occlusion pressure and periodically deflating the cuff to detect amplitude of oscillometric oscillations reaching or exceeding a predetermined threshold, whereby indicating that the cuff pressure has reached an updated systolic blood pressure. Selecting the cuff to be wide enough to define limb occlusion pressure at or below the systolic blood pressure assures that this maneuver does not compromise cessation of blood flow to the limb. Devices are disclosed configured to operate in at least two of the following three operating modes: a tourniquet mode, a remote conditioning mode and a blood pressure monitoring mode.

主权项

1. A method for adaptive limb occlusion of a subject, the method comprising the steps of:
(a) providing a cuff sized to be placed about a limb of the subject, said cuff is configured to define a limb occlusion pressure to be equal to or below a systolic blood pressure of the subject; (b) determining the systolic blood pressure of the subject by inflating the cuff placed about the same limb of the subject; (c) inflating the cuff to a pressure sufficient to cause cessation of blood flow through the same limb, said pressure being below, at or above the systolic blood pressure calculated in step (b) for a period of cuff inflation, said period of cuff inflation lasting at least about one minute; (d) at least once during the period of cuff inflation, decreasing entire cuff pressure until detecting an increase in oscillometric oscillations indicating the cuff pressure to be above, equal to, and capable of being below an updated systolic blood pressure while at least equal to or being above the corresponding limb occlusion pressure of the subject, whereby said entire cuff pressure is decreased sufficiently to determine the updated systolic blood pressure of the subject but without compromising cessation of blood flow through the same limb; and (e) inflating the cuff to a pressure below, at or above the updated systolic blood pressure calculated in step (d), said pressure being sufficient to continue causing cessation of blood flow through the same limb.