发明名称 |
LINEAR PEPTIDE ANTIBIOTICS. |
摘要 |
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broad spectrum of antibiotic bioactivity. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided. |
申请公布号 |
MX2014009899(A) |
申请公布日期 |
2015.03.09 |
申请号 |
MX20140009899 |
申请日期 |
2013.02.15 |
申请人 |
RQX PHARMACEUTICALS, INC. |
发明人 |
ROBERT I. HIGUCHI;TUCKER CURRAN ROBERTS;PETER ANDREW SMITH;DAVID CAMPBELL;PRASUNA PARASELLI |
分类号 |
C07C233/05;A61K31/16;A61P31/00;C07D207/08 |
主分类号 |
C07C233/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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