发明名称 |
Revestimientos de dispositivos médicos para liberar un agente terapéutico a diferentes velocidades |
摘要 |
<p>Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodiment, medical device coatings are provided having a higher concentration of the therapeutic agent in a first region of the coating than in a second region of the coating. In a third embodiment, medical device coatings are provided that are formed by certain coating processes wherein the droplet size of a spray coating solution is changed during the coating process. These coating processes preferably include applying a solution comprising a therapeutic agent and a suitable solvent to a surface of an implantable medical device. In a fourth embodiment, methods of treatment are provided that include implanting a coated medical device.</p> |
申请公布号 |
ES2530862(T3) |
申请公布日期 |
2015.03.06 |
申请号 |
ES20080725134T |
申请日期 |
2008.02.04 |
申请人 |
COOK MEDICAL TECHNOLOGIES LLC |
发明人 |
SHIRLEY, GARY BRADFORD;MOORE, WILLIAM F. |
分类号 |
A61F2/958;A61L27/34;A61L27/54;A61L31/10;A61L31/16 |
主分类号 |
A61F2/958 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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