NEUROFIBROMATOSES THERAPEUTIC AGENTS AND SCREENING FOR SAME

摘要

Disclosed herein are methods of treating a patient at risk of developing or having a neurofibromatosis or a sporadic schwannoma. In exemplary embodiments, the method involves administering to a subject in need an effective amount of a modulator of a target related to neurofibromatosis. Also disclosed are screening assays involving the implementation of Merlin-null Schwann cells, and to compounds identified using same.

主权项

1. A method for treating a neurofibromatosis in a subject, the method comprising administering to the subject an effective amount of a NF-related agent.