| 摘要 |
<p>An isosorbide preparation of this invention is characterized in that a pharmaceutical composition containing crystalline isosorbide with a water content of 0.5% by weight or less (except for the case where those with a particle size less than 355 µm are contained in a proportion of 85% by weight or more) and a lubricant is packaged with a water impermeable packaging material containing aluminum. This can stably maintain the pharmaceutical composition containing crystalline isosorbide which is highly hygroscopic and highly caking for a long period of time and the isosorbide preparation excellent also in portability is provided.</p> |
