METHODS TO PRODUCE BOLAAMPHIPHILIC GLYCOLIPIDS

摘要

The present invention relates to the field of the microbial production of specific types of glycolipids which are potentially useful as replacements for petroleum-based detergents and emulsifiers. More specifically the present invention discloses the usage of yeasts having a dysfunctional acetyltransferase for producing high amounts of bolaamphiphilic glycolipids when using conventional and cheap substrates. Furthermore, the present invention relates to yeasts having a dysfunctional acetyltransferase optionally combined with a dysfunctional lactonase and/or second glucosyltransferase. The latter microorganisms are capable to produce high amounts of bolaamphiphilic sophorolipids.