| 发明名称 |
SALTS OF 5-[(1R)-2-(AMINO)-1-HYDROXYETHYL]-8-HYDROXYQUINOLIN-2(1H)-ONE |
| 摘要 |
The present invention is directed to a pharmaceutically acceptable crystalline addition salt of 5-[(1R)-2-({2-[4-({4-(2,2-difluoro-2-phenylethoxy)phenyl]ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one, and (ii) a dicarboxylic acid, a sulfonic acid or a sulfimide, or a pharmaceutically acceptable solvate thereof. |
| 申请公布号 |
US2015065471(A1) |
申请公布日期 |
2015.03.05 |
| 申请号 |
US201314389843 |
申请日期 |
2013.03.28 |
| 申请人 |
ALMIRALL, S.A. |
发明人 |
Puig Duran Carlos;Carrera Carrera Francesc;Pérez Garcia Juan Bautista;Moyes Valles Enrique;Marchueta Hereu Iolanda |
| 分类号 |
C07D215/26;C07C55/10;A61K31/56;C07D275/06;A61K31/4704;A61K45/06;C07C57/15;C07C309/04 |
主分类号 |
C07D215/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutically acceptable crystalline addition salt of (i) 5-[(1R)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl]ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one, and (ii) a dicarboxylic acid, a sulfonic acid or a sulfimide, or a pharmaceutically acceptable solvate thereof. |
| 地址 |
Barcelona ES |
