| 发明名称 |
NANOPARTICLES FOR CONTROLLED LYSIS OF BLOOD CLOTS |
| 摘要 |
Fibrinolytic nanoparticles including a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and a fibrinolytic agent dispersed within the core, are described herein. The fibrinolytic nanoparticles can be used in method of dissolving a blood clot in a subject by administering to the subject a therapeutically effective amount of fibrinolytic nanoparticles. |
| 申请公布号 |
US2015064267(A1) |
申请公布日期 |
2015.03.05 |
| 申请号 |
US201414471616 |
申请日期 |
2014.08.28 |
| 申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
Ramamurthi Anand;Sivaraman Balakrishnan;Sylvester Andrew |
| 分类号 |
A61K9/51;A61K38/48 |
主分类号 |
A61K9/51 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A fibrinolytic nanoparticle comprising a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and a fibrinolytic agent dispersed within the core. |
| 地址 |
Cleveland OH US |
