发明名称 |
PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMININISTRATION OF HYDROPHOBIC DRUGS |
摘要 |
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs are provided. The pharmaceutical compositions include a therapeutically effective amount of a hydrophobic drug, preferably a steroid; a solubilizer, and a surfactant. The synergistic effect between the hydrophobic drug and the solubilizer results in a pharmaceutical formulation with improved dispersion of both the active agent and the solubilizer. As a result of the improved dispersion, the pharmaceutical composition has improved bioavailability upon administration. Methods of improving the bioavailability of hydrophobic drugs administered to a patient are also provided. |
申请公布号 |
US2015064243(A1) |
申请公布日期 |
2015.03.05 |
申请号 |
US201414535536 |
申请日期 |
2014.11.07 |
申请人 |
Lipocine Inc. |
发明人 |
Chen Feng-Jing;Patel Mahesh V.;Fickstad David T.;Zhang Huiping;Giliyar Chandrashekar |
分类号 |
A61K47/22;A61K9/48;A61K47/12;A61K31/5685;A61K47/08 |
主分类号 |
A61K47/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Salt Lake City UT US |