| 发明名称 |
ANTIBODIES TO TUMOR ENDOTHELIAL MARKER 7R |
| 摘要 |
Antibodies that specifically bind to an epitope on the extracellular domain of TEM7R are provided. Nucleic acids encoding such antibodies and cells capable of expressing such antibodies are also provided. The antibodies may be used in methods for treating tumors and for inhibiting angiogenesis in tumors. |
| 申请公布号 |
US2015064190(A1) |
申请公布日期 |
2015.03.05 |
| 申请号 |
US201414514493 |
申请日期 |
2014.10.15 |
| 申请人 |
Institute for Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center |
发明人 |
Borghaei Hossein;Weiner Louis M. |
| 分类号 |
C07K16/28;A61K47/48 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated antibody that specifically binds to an epitope on the extracellular domain of TEM7R, comprising a heavy chain variable region having 95% sequence identity with the amino acid sequence of SEQ ID NO: 9. |
| 地址 |
Philadelphia PA US |
