发明名称 |
DABIGATRAN ETEXILATE SYNTHESIZING METHOD |
摘要 |
<p>The present invention relates to a dabigatran etexilate synthesizing method, the method being characterized by: using 2-(hydroxymethyl)-1H-benzimidazole -5-carboxy acid as raw material, thus greatly reducing the raw material and reagent costs for synthesizing benzimidazole, and having considerable economic value and market competitiveness; and not discharging a great deal of waste acid in a reaction process, thus having environmental value, and providing an optimal solution for large-scale industrial production of dabigatran etexilate.</p> |
申请公布号 |
WO2015027893(A1) |
申请公布日期 |
2015.03.05 |
申请号 |
WO2014CN85156 |
申请日期 |
2014.08.26 |
申请人 |
HYBIO PHARMACEUTICAL CO., LTD. |
发明人 |
CHEN, XINLIANG;LI, GUOTAO;MA, YAPING;YUAN, JIANCHENG |
分类号 |
C07D401/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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