发明名称 DABIGATRAN ETEXILATE SYNTHESIZING METHOD
摘要 <p>The present invention relates to a dabigatran etexilate synthesizing method, the method being characterized by: using 2-(hydroxymethyl)-1H-benzimidazole -5-carboxy acid as raw material, thus greatly reducing the raw material and reagent costs for synthesizing benzimidazole, and having considerable economic value and market competitiveness; and not discharging a great deal of waste acid in a reaction process, thus having environmental value, and providing an optimal solution for large-scale industrial production of dabigatran etexilate.</p>
申请公布号 WO2015027893(A1) 申请公布日期 2015.03.05
申请号 WO2014CN85156 申请日期 2014.08.26
申请人 HYBIO PHARMACEUTICAL CO., LTD. 发明人 CHEN, XINLIANG;LI, GUOTAO;MA, YAPING;YUAN, JIANCHENG
分类号 C07D401/12 主分类号 C07D401/12
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