摘要 |
Compounds are disclosed that have a formula represented by Formula (I) wherein A, B, R1, R2 and R3 are as defined herein. Novel compounds of the invention may be prepared as a pharmaceutical composition, and may be useful in the treatment of infectious diseases, in particular bacterial infectious diseases. The compounds may be active against a specific enzyme in the bacterial DNA replicative process, DNA polymerase IIIE. |
申请人 |
GALAPAGOS NV |
发明人 |
DUDFIELD, PHILIP JOHN;LOWTHER, JOHN;DELACHAUME, CAROLE ANNIE JOSETTE;LÉPINE, RENAUD HENRI MARCEL;ROTH DIT BETTONI, ROMAIN VINCENT RAPHAËL;GUILLAUME, JULIE MARIE-HÉLÈNE MARTHE;THYS, AMBER PAULA MARCELLA;BARON, ANNE CATHERINE;CANOVA, SOPHIE LUCIENNE JEANNE;WITZIG, ROBERT;DOYON, JULIEN GEORGES PIERRE-OLIVIER;TOUMI, MATHIEU PAUL;HANSSKE, FRIEDRICH GEORG |