USE OF AMIDES OF MONO- AND DICARBOXYLIC ACIDS IN THE TREATMENT OF RENAL DISEASES

摘要

A therapy for renal diseases, in particular renal diseases, which develop in diabetic patients or patients who have been subjected to a treatment with an antitumor chemotherapy such as a platinum derivative and more generally cytotoxic drugs at renal level for treating of neoplastic diseases. More particularly, palmitoylethanolamide and diethanolamide of fumaric acid are used in the treatment of renal diseases, in particular those caused by dysmetabolic diseases or by toxic or chemotherapy agents, such as platinum derivatives. Palmitoylethanolamide is used preferably in micronized or ultra-micronized form. Diethanolamide of fumaric acid is used preferably in aqueous solution.

主权项

1. A method of treating renal diseases, consisting essentially of administering a therapeutically effective amount of diethanolamide of fumaric acid to a patient in need thereof, wherein said renal diseases are selected from among:
Diabetic nephropathy Nephroangiosclerosis Polycystic renal disease (polycystic kidney) Immunoglobulin A nephropathy Tubular necrosis Glomerulonephritis Urethral stenosis Iatrogenous nephropathies (from NSAIDs, from cytotoxic drugs, from Lithium, from antibiotics, from Cyclosporine) Nephropathies from therapeutic radiations Nephropathies of the aged.