发明名称 |
HIGH EFFICIENCY MICROFLUIDIC PURIFICATION OF STEM CELLS TO IMPROVE TRANSPLANTS |
摘要 |
Described herein is a novel, highly efficient system to remove erythrocytes and purify leukocytes would raise the quality of UCB and other transplant grafts, thereby significantly improving patient outcomes. |
申请公布号 |
US2015064153(A1) |
申请公布日期 |
2015.03.05 |
申请号 |
US201414212885 |
申请日期 |
2014.03.14 |
申请人 |
THE TRUSTEES OF PRINCETON UNIVERSITY ;UNIVERSITY OF MARYLAND, BALTIMORE |
发明人 |
Civin Curt I.;Sturm James C.;Austin Robert H. |
分类号 |
C12N5/0789;A61K35/28;A61K35/14;C12N5/078;C12N5/0787 |
主分类号 |
C12N5/0789 |
代理机构 |
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代理人 |
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主权项 |
1. A method for isolating stem cells from a sample for transplantation, the method comprising:
(a) providing a sample comprising erythrocytes and leukocytes, the sample having a volume of less than 300 mL; (b) depleting the erythrocytes; and (c) enriching the leukocytes to a purity of at least 90%. |
地址 |
Princeton NJ US |