发明名称 |
APPLICATION OF DMAP HYDROCHLORIDE SERVING AS RECYCLABLE CATALYST IN ACYLATION REACTION |
摘要 |
<p>The present invention relates to an application of dimethylaminopyridine (DMAP) hydrochloride serving as recyclable catalyst in an acylation reaction (as represented by equation I). The application comprises: dissolving DMAP into a nonpolar solvent, aerating with dry hydrogen chloride gas, and filtrating the solution to obtain DMAP hydrochloride; adding a catalytic amount of DMAP hydrochloride to inert alcohol, phenol and amine under a solvent-free or organic solvent condition, and completely reacting with an acylation reagent at 0-130 ℃; adding a nonpolar solvent, and filtrating the recyclable catalyst, that is, the DMAP hydrochloride; and conducting washing, caustic scrubbing, liquid separation and organic phase drying on the filtrate, and evaporating and removing the solvent to obtain the acylated product. The recycled DMAP hydrochloride can be used in the next catalytic cycle.</p> |
申请公布号 |
WO2015027773(A1) |
申请公布日期 |
2015.03.05 |
申请号 |
WO2014CN82340 |
申请日期 |
2014.07.16 |
申请人 |
NANKAI UNIVERSITY;JIANGSU ANPON ELECTROCHEMICAL CO., LTD |
发明人 |
JIANG, YUTIAN;WANG, QINGMIN;LIU, ZHIHUI;MA, QIAOQIAO;LIU, YUXIU;JI, YUXIANG;ZHAO, WEIDONG |
分类号 |
C07C255/46;B01J31/02;C07C67/08;C07C67/14;C07C69/14;C07C69/157;C07C69/63;C07C69/67;C07C69/757;C07C69/78;C07C201/12;C07C205/43;C07C231/02;C07C233/92;C07C253/30;C07D213/64;C07D213/74;C07D215/22;C07D233/90;C07D311/52 |
主分类号 |
C07C255/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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