发明名称 GITR ANTIGEN BINDING PROTEINS
摘要 Antigen binding proteins that activate GITR are provided. Nucleic acids encoding the antigen binding proteins and vectors and cells containing such nucleic acids are also provided. The antigen binding proteins have value in therapeutic methods in which it is useful to stimulate GITR signaling, thereby inducing or enhancing an immune response in a subject. Accordingly, the antigen binding proteins have utility in a variety of immunotherapy treatments, including treatment of various cancers and infections.
申请公布号 CA2922808(A1) 申请公布日期 2015.03.05
申请号 CA20142922808 申请日期 2014.08.28
申请人 AMGEN INC. 发明人 BEERS, COURTNEY;O'NEILL, JASON C.;FOLTZ, IAN NEVIN;KETCHEM, RANDAL R.;PIASECKI, JULIA C.
分类号 C07K16/28;A61K39/395;A61K45/06 主分类号 C07K16/28
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