发明名称 |
Hydroxamate substituted azaindoline-cyanine dyes and bioconjugates of the same |
摘要 |
Hydroxamate substituted azaindoline cyanine dyes, conjugates thereof and methods of using the same are provided. The subject cyanine dyes include an azaindoline ring having a hydroxamate substituent. The dyes may further include a reactive group moieties (RGM) and/or a water soluble group. Also provided are conjugates of the subject dyes. Also provided are tandem conjugates including a fluorescent protein capable of energy transfer to the dye. Methods of detecting an analyte in a sample by contacting the sample with a detection reagent are provided. The detection agent may be a dye-conjugate that specifically binds the analyte, or may be a reactive dye which conjugates to the analyte. Also provided are compositions, e.g., kits, etc., incorporating such dyes which facilitate use in such methods. |
申请公布号 |
AU2013334635(A1) |
申请公布日期 |
2015.03.05 |
申请号 |
AU20130334635 |
申请日期 |
2013.10.23 |
申请人 |
BECTON, DICKINSON AND COMPANY |
发明人 |
DIWU, ZHENJUN;GUO, HAITAO;HAN, XING;SCHULTZ, MIRION;DUBROVSKY, TIMOTHY |
分类号 |
G01N33/532;G01N33/533;G01N33/58 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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