| 发明名称 |
NANOPARTICLES FOR STIMULATING ELASTOGENESIS |
| 摘要 |
Elastogenic nanoparticles including a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and comprising an active agent having pro-elastogenic and/or anti-proteolytic activity, are described herein. The elastogenic nanoparticles can be used in method of stimulating elastogenesis in a subject by administering to the subject a therapeutically effective amount of elastogenic nanoparticles. |
| 申请公布号 |
US2015064268(A1) |
申请公布日期 |
2015.03.05 |
| 申请号 |
US201414471508 |
申请日期 |
2014.08.28 |
| 申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
Ramamurthi Anand;Sivaraman Balakrishnan |
| 分类号 |
A61K31/14;A61K9/51;A61K41/00;A61K31/65;A61K47/48 |
主分类号 |
A61K31/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An elastogenic nanoparticle comprising a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and comprising an active agent having pro-elastogenic and/or anti-proteolytic activity. |
| 地址 |
Cleveland OH US |
