发明名称 |
METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS |
摘要 |
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents. |
申请公布号 |
EP2729180(A4) |
申请公布日期 |
2015.03.04 |
申请号 |
EP20120810577 |
申请日期 |
2012.07.09 |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
LIN, WENBIN;LIU, DEMIN;DELLA ROCCA, JOSEPH;KRAMER, STEPHANIE, A.;POON, CHRISTOPHER, Y. |
分类号 |
A61K47/48;A61K9/127;A61K9/14;A61K9/16;A61K9/51;A61K31/663;A61K31/675;A61K49/00;A61K49/06;A61K49/08;A61K51/12;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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