METHOD FOR DETERMINING READ ERROR IN NUCLEOTIDE SEQUENCE

摘要

A method is a method for determining whether a difference between a first reference sequence and first comparative sequences sharing homology with the first reference sequence is caused by a mutation of the first comparative sequence or caused by a read error in sequencing. The method includes generating second comparative sequences and a second reference sequence by substituting a sequence having a predetermined base number or more of consecutive same bases for a sequence having the predetermined base number of the consecutive same bases in the first comparative sequences and the first reference sequence (S103). The method further includes calculating an edit distance of the second comparative sequence with respect to the second reference sequence (S104), and determining whether the difference is caused by the mutation or caused by the read error based on the edit distance (S105).