摘要 |
<p>A method for controlling the supply of ions from a Liquid Chromatograph through an ion source and into a Mass Spectrometer is disclosed comprising the steps of operating the ion source in a first mode where eluant produced in the LC passes through a probe into a source volume but is prevented from entering an inlet of the MS in an ionized form, changing one or more operating parameters of the ion source and operating the ion source in a second mode where at least some ions are produced in said ion source and pass through said MS inlet into the MS.</p> |