NOVEL INTEGRIN alpha9beta1 LIGAND AND USES THEREOF

摘要

Provided is a novel ligand for integrin ±9²1 consisting of a peptide having the following amino acid sequence:
(A) EDDMMEVPY (SEQ ID NO: 1) or
(B) an amino acid sequence the same as the amino acid sequen ce represented by SEQ ID NO: 1 except for having deletion, s ubstitution or addition of 1 to 3 amino acids. The novel lig and for integrin ±9²1 has a higher binding affinity than tho se of tenascin-C and osteopontin, which are known ligands fo r integrin ±9²1.