| 发明名称 | Process for preparing nebivolol | ||
| 摘要 | The present invention relates to a process for preparing Nebivolol and, more in particular, to a fractional distillation method of a mixture of stereoisomers of formula; intermediates useful in the preparation of nebivolol. | ||
| 申请公布号 | US8969597(B2) | 申请公布日期 | 2015.03.03 |
| 申请号 | US201013383108 | 申请日期 | 2010.07.23 |
| 申请人 | Zach System S.p.A. | 发明人 | Cotarca Livius;Foletto Johnny;Maragni Paolo;Soriato Giorgio;Urbani Daniele;Verzini Massimo |
| 分类号 | C07D407/04;C07D311/74 | 主分类号 | C07D407/04 |
| 代理机构 | Silvia Salvadori, P.C. | 代理人 | Silvia Salvadori, P.C. |
| 主权项 | 1. A process for obtaining a compound of formula as a diastereoisomerically pure compound of RS/SR configuration, and a compound of formula as a diastereoisomerically sure com ound of RR/SS configuration, said method comprising: separating a compound of formula by fractional distillation; and obtaining said compound of formula as a diastereoisomerically pure compound of RS/SR configuration; and said compound of formula as a diastereoisomerically pure compound of RR/SS configuration. | ||
| 地址 | Bresso IT | ||