| 主权项 |
1. A pharmaceutical composition comprising a 11-deoxy-prostaglandin compound represented by formula (III): wherein L is hydrogen, hydroxy, halogen, lower alkyl, hydroxy(lower)alkyl, lower alkanoyloxy or oxo, wherein the five-membered ring may optionally have at least one double bond; A is —CH3, —CH2OH, —COCH2OH, —COOH or a functional derivative thereof; B is single bond, —CH2—CH2—, —CH═CH—, —C≡C—, —CH2—CH2—CH2—, —CH═CH—CH2—, —CH2—CH═CH—, —C≡C—CH2— or —CH2—C≡C—; R1 is a saturated or unsaturated bivalent lower or medium aliphatic hydrocarbon, which is unsubstituted or substituted with halogen, lower alkyl, hydroxy, oxo, aryl or heterocyclic group, and at least one of carbon atom in the aliphatic hydrocarbon is optionally substituted by oxygen, nitrogen or sulfur; R2 is a single bond or lower alkylene; R3 is lower alkyl, lower alkoxy, lower alkanoyloxy, cyclo(lower)alkyl, cyclo(lower)alkyloxy, aryl, aryloxy, heterocyclic group or heterocyclic-oxy group, and at least one carbon atom in the aliphatic hydrocarbon is optionally substituted by oxygen, nitrogen or sulfur; X1 and X2 are hydrogen, lower alkyl, or halogen; and Z is ═O, and a fatty acid ester derived from (1) a fatty acid and (2) glycerine. |
