| 发明名称 | Stabilized pharmaceutical composition | ||
| 摘要 | The invention relates to stabilized pharmaceutical composition comprising pregabalin and a disaccharide or higher polyol as stabilizer and optionally a conventional pharmaceutically acceptable carrier. The stabilized pharmaceutical composition according to the invention is useful in the treatment of a number of diseases such as epilepsy, Alzheimer's disease or Parkinson's disease. | ||
| 申请公布号 | US8968780(B2) | 申请公布日期 | 2015.03.03 |
| 申请号 | US201113582162 | 申请日期 | 2011.03.01 |
| 申请人 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | 发明人 | Yadav Kamala S.;Surana Amita P.;Kulkarni Sanjivani A.;Prasade Rashmi R. |
| 分类号 | A61K9/28;A61K9/16;A61K31/197 | 主分类号 | A61K9/28 |
| 代理机构 | Lucas & Mercanti, LLP | 代理人 | Lucas & Mercanti, LLP ;Myers Jonathan |
| 主权项 | 1. A stabilized solid pharmaceutical composition, in powder form as a capsule filled with powder or as a tablet, suitable for oral administration, consisting of about 10% to about 99% by weight pregabalin and about 0.01% to about 75% by weight isomalt as stabilizer in an amount effective to stabilize the pregabalin against lactam formation, and optionally a pharmaceutically acceptable inert carrier. | ||
| 地址 | Budapest HU | ||