发明名称 |
Compounds for the inhibition of cellular proliferation |
摘要 |
Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein. |
申请公布号 |
US8969573(B2) |
申请公布日期 |
2015.03.03 |
申请号 |
US201113807132 |
申请日期 |
2011.06.28 |
申请人 |
President and Fellows of Harvard College |
发明人 |
Chorev Michael;Aktas Bertal Huseyin;Halperin Jose A.;Wagner Gerhard |
分类号 |
C07D417/02;C07D277/38;C07D241/02;A61K31/381;A61K31/496;C07D277/84;C07D233/88;C07D263/48;C07D277/50;C07D417/04;C07D417/10;C07D417/12;C07D277/30;C07D277/42;C07D513/04 |
主分类号 |
C07D417/02 |
代理机构 |
Banner & Witcoff, Ltd. |
代理人 |
Banner & Witcoff, Ltd. |
主权项 |
1. A compound having the structure |
地址 |
Cambridge MA US |