Individually adapted cardiac electro-mechanical synchronization therapy

摘要

A method of determining pacing therapy for an individual patient including determining representative electromechanical physiologic characteristics for a plurality of normal patients having a range of anatomical dimensions and developing a plurality of normal templates. Each template indicates the representative electromechanical physiologic characteristics of a group of normal patients having similar anatomical dimensions. The method can include measuring the anatomical dimensions of a dysfunctional patient, matching the dysfunctional patient with a template for normal patients having similar anatomical dimensions as the dysfunctional patient, determining the physiologic characteristics for the dysfunctional patient, determining indicated correction factors corresponding to any differences between the dysfunctional patient's physiologic characteristics and those of the matched template, and adjusting therapy delivery by any indicated correction factors to stimulate the patient in a pattern more closely matched to the physiologic characteristics of the matched template.

主权项

1. A method of adjusting an implantable resynchronization therapy device for adaptation to the needs of an individual patient, the method comprising:
measuring a plurality of physiologic parameters of a cardiomyopathy patient at least partially via an implantable device; obtaining data indicative of corresponding cardiac anatomical dimensions for a matched group of at least one eufunctional patient; comparing the plurality of measured physiologic parameters of the cardiomyopathy patient with data indicative of corresponding cardiac anatomical dimensions for a matched group of at least one eufunctional patient, the data being stored by the implantable device; and dynamically adjusting resynchronization therapy delivery by the device such that the plurality of physiologic parameters of the cardiomyopathy patient are brought into closer conformance with those of the matched group of at least one eufunctional patient.