Nitrogen containing compounds and their use

摘要

Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.;

主权项

1. A process for preparation of a compound of Formula (I), said process comprising: a) converting a compound of Formula (II) to a compound of Formula (III); b) reacting a compound of Formula (III) with di-tert-butyldicarbonate in presence of triethylamine and N,N-dimethylamino pyridine to obtain a compound of Formula (IV); c) reacting a compound of Formula (IV) with trifluoroacetic anhydride to obtain a compound of Formula (V); d) converting a compound of Formula (V) to a compound of Formula (VI); e) reacting a compound of Formula (VI) with O-benzylhydroxylamine hydrochloride to obtain a compound of Formula (VII); f) reacting a compound of Formula (VII) with methanesulphonic acid, followed by treatment with potassium hydrogen carbonate to obtain a compound of Formula (IX); g) converting a compound of Formula (IX) to a compound of Formula (XII); h) cyclizing a compound of Formula (XII) to obtain a compound of Formula (XIII); and i) converting a compound of Formula (XIII) to a compound of Formula (I).