| 发明名称 | Bispecific aptamers mediating tumour cell lysis | ||
| 摘要 | Disclosed are bispecific aptamers binding with high specifity to a tumour specific antigen (TSA) and a effector cell specific antigen (ESA) for treatment of cancer. | ||
| 申请公布号 | US8969318(B2) | 申请公布日期 | 2015.03.03 |
| 申请号 | US201113992608 | 申请日期 | 2011.12.12 |
| 申请人 | Merck Patent GmbH | 发明人 | Toleikis Lars;Guenther Ralf;Hock Bjoern;Doerner Achim |
| 分类号 | A61K48/00;C07H21/02;C07H21/04;C12Q1/68 | 主分类号 | A61K48/00 |
| 代理机构 | Millen, White, Zelano, Branigan, P.C. | 代理人 | Millen, White, Zelano, Branigan, P.C. |
| 主权项 | 1. A bispecific aptamer which specifically binds to a tumor related antigen (TRA) which is c-Met and an effector specific antigen (ESA) which is CD16a. | ||
| 地址 | Darmstadt DE | ||