Microanalysis methods and systems using field effect transistor

摘要

Provided is a microanalysis method and system using a Field Effect Transistor (FET). The microanalysis method includes a channel region having a receptor molecule fixed; forming a nano-particle conjugate in the channel region by supplying a sample for test and the nano-particle conjugate to the FET; growing a probe material on the channel region; and measuring a current flowing through the channel region, wherein the receptor molecule is a material that is selectively bonded to a target molecule in the sample for test.

主权项

1. A microanalysis method comprising:
preparing a Field Effect Transistor (FET) including a channel region that has a receptor molecule, the receptor molecules being fixed on a surface of the channel region; supplying a sample and a solution to the FET, the sample including a target molecule and the solution including a nano-particle conjugate; binding the target molecule to the receptor molecule; binding the nano-particle conjugate to the target molecule; measuring a first current through the channel region after binding the target molecule to the receptor molecule and before growing a probe material; growing the probe material on the channel region of the FET such that the probe material binds to the nano-particle conjugate; measuring a second current through the channel region after growing the probe material; calculating a difference between the first current and the second current; and obtaining a concentration of the target molecule based on the calculated difference.