Pyrazolopyrimidine compounds and their use as PDE10 inhibitors

摘要

The present invention relates to a compound represented by formula [I]:;
wherein:
R1 is hydrogen, halogen, lower alkyl or cyano;Ring A is an optionally substituted heterocyclic group;Ring B is an optionally substituted 3 to 6-membered monocyclic group; andY is optionally substituted amino, optionally substituted cyclic amino, optionally substituted aliphatic 3 to 6-membered monocyclyloxy, optionally substituted lower alkyl or optionally substituted lower alkyl-O—,

or a pharmaceutically acceptable salt thereof, and to their use as PDE10 inhibitor.

主权项

1. A compound represented by formula [I]: wherein:
R1 is hydrogen, halogen, lower alkyl or cyano;Ring A is an optionally substituted heterocyclic group;Ring B is an optionally substituted 3 to 6-membered monocyclic group; andY is optionally substituted amino,optionally substituted cyclic amino,optionally substituted aliphatic 3 to 6-membered monocyclyloxy,optionally substituted lower alkyl oroptionally substituted lower alkyl-O—, or a pharmaceutically acceptable salt thereof.