发明名称 Processes for the preparation of highly pure plasmid compositions by enzymatic digestion of colanic acid
摘要 A process for the purification of plasmid DNA, the process comprising treating an aqueous composition containing plasmid DNA with a polypeptide obtained from an NST1 phage to digest colanic acid and separating the plasmid DNA from the treated aqueous composition.
申请公布号 US8969068(B2) 申请公布日期 2015.03.03
申请号 US200912433674 申请日期 2009.04.30
申请人 Gradalis, Inc. 发明人 Templeton Nancy Smyth
分类号 C12P1/00;C12S3/00;C12N9/24;C12N15/10;C07H21/04;C12N15/63 主分类号 C12P1/00
代理机构 Chalker Flores, LLP 代理人 Flores Edwin S.;Chalker Flores, LLP
主权项 1. A process for the purification of plasmid DNA, the process comprising treating an aqueous composition containing plasmid DNA with a polypeptide to digest colanic acid and separating the plasmid DNA from the treated aqueous composition, wherein the polypeptide comprises SEQ ID NOS: 1 or 2.
地址 Dallas TX US