| 发明名称 |
BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR TREATING CANER AND IMMUNE DISEASES |
| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to specific compounds or to their therapeutically acceptable salt presented in the patent claim and representing sulphonyl benzamide derivatives. The invention also refers to a pharmaceutical composition inhibiting the activity of anti-apoptotic proteins of the family Bcl-2, containing an excipient and an effective amount of a specific sulphonyl benzamide derivative.EFFECT: sulphonyl benzamide derivatives inhibiting the activity of anti-apoptotic Bcl-2 proteins.2 cl, 3 tbl, 558 ex |
| 申请公布号 |
RU2542994(C2) |
申请公布日期 |
2015.02.27 |
| 申请号 |
RU20120127760 |
申请日期 |
2010.06.01 |
| 申请人 |
EHBBVI INK. |
发明人 |
BRANKO MILAN;DIN KHUN;DOUEHRTI DZHORDZH A.;EHLMOR STIVEN V.;KHASVOL'D LIZA;KHEKSAMER LAURA;KANZER AARON;MANTEJ ROBERT A.;MAKKLELLAN UILL'JAM DZH.;PARK CHANG KH.;PARK CHEHOL-MIN;PETROS EHNDRJU M.;SUN SJAOKHUN;SAUEHRS EHNDRJU DZH.;SALLIVAN DZHERARD M.;TAO CHZHI-FU;VAN GARI T.;VAN LEH;VAN SILU;UEHNDT MAJKL D.;KHANSEN TODD M. |
| 分类号 |
C07D405/12;A61K31/416;A61K31/4184;A61K31/4192;A61K31/427;A61K31/4427;A61P35/00;C07D211/96;C07D213/64;C07D231/56;C07D235/26;C07D249/18;C07D401/12;C07D403/12;C07D403/14;C07D405/14;C07D417/14 |
主分类号 |
C07D405/12 |
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