发明名称 Crystalline forms of an alkoxyimidazol-1-ylmethyl biphenyl carboxylic acid
摘要 <p>The disclosure relates to crystalline salt forms, namely the hemi-edisylate and hemi-napadisylate forms of 4’-{ 2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl} -3’-fluorobiphenyl-2-carboxylic acid. The disclosure also relates to pharmaceutical compositions comprising these crystalline forms, methods for forming them and methods of using the crystalline forms in medicaments for the treatment of diseases such as heart disease or hypertension.</p>
申请公布号 NZ609804(A) 申请公布日期 2015.02.27
申请号 NZ20110609804 申请日期 2011.11.09
申请人 THERAVANCE BIOPHARMA R&D IP LLC 发明人 FATHEREE PAUL R.;THALLADI VENKAT R.
分类号 C07D233/70;A61K31/4174;A61P9/00 主分类号 C07D233/70
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