发明名称 Trpv4 antagonists
摘要 <p>The present disclosure relates to spirocarbamate compounds of Formula (I) in which R1, (R2)Y, R3, R4, X and A have the meanings given in the specification. The disclosure further provides pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and relates to their use of these compounds as TRPV4 antagonists in treating or preventing conditions associated with TRPV4 imbalance.</p>
申请公布号 NZ618221(A) 申请公布日期 2015.02.27
申请号 NZ20120618221 申请日期 2012.06.15
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED 发明人 BROOKS CARL;EIDAM HILARY SCHENCK;GOODMAN KRISTA B.;HAMMOND MARLYS;HILFIKER MARK A.;HOANG TRAM H.;PATTERSON JACLYN R.;STOY PATRICK;YE GUOSEN;CHEUNG MUI
分类号 C07D263/52;A61K31/423;A61P9/04;A61P11/00;C07D413/14;C07D417/14;C07D419/14;C07D495/04;C07D498/00 主分类号 C07D263/52
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