MCP-1 BINDING NUCLEIC ACID AND USING IT

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions refers to biotechnology and medicine. Administering into an individual a nucleic acid molecule, which is able to bind to MCP-1 and is an MCP-1 antagonist, wherein the nucleic acid molecule contains the nucleic acid sequence SEQ ID NO:37 in a combination with an immunosuppressive agent, for treating lupus nephritis enables reducing a dose of the immunosuppressive agent.EFFECT: administering into the individual the nucleic acid molecule, wherein the nucleic acid molecule contains the nucleic acid sequence SEQ ID NO:37 has a therapeutic effect in treating pulmonary hypertension and chronic obstructive pulmonary disease.30 cl, 54 dwg, 1 tbl, 12 ex