IMIDAZOPYRIDIN-2-ONE DERIVATIVES

摘要

THERE IS PROVIDED A COMPOUND REPRESENTED BY THE FOLLOWING FORMULA (I) HAVING MTOR INHIBITORY ACTIVITY OR A PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF. [IN THE FORMULA (I), A IS A 8- TO 10-MEMBERED PARTIALLY SATURATED OR AROMATIC FUSED BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC GROUP HAVING 1 TO 3 NITROGEN ATOMS, R1 IS A HYDROXY GROUP, A HALOGEN ATOM, A CYANO GROUP OR THE LIKE, N IS ANY INTEGER OF 0 TO 3, B IS A 3- TO 7-MEMBERED MONOCYCLIC SATURATED OR PARTIALLY SATURATED CYCLIC HYDROCARBON GROUP AND MAY CONTAIN 1 OR 2 OXYGEN ATOMS, SULFUR ATOMS, NITROGEN ATOMS OR THE LIKE AS RING CONSTITUENTS, R2 IS A SUBSTITUENT PRESENT ON A CARBON ATOM OR NITROGEN ATOM FORMING B, M IS ANY INTEGER OF 0 TO 3, Q IS A BOND OR A C1-4 ALKYLENE GROUP, R3 AND R4 ARE THE SAME OR DIFFERENT AND ARE EACH A HYDROGEN ATOM, A HALOGEN ATOM, A C1-4 ALKYL GROUP OR THE LIKE, AND R5 AND R6 ARE THE SAME OR DIFFERENT AND ARE EACH A HYDROGEN ATOM, A HALOGEN ATOM, A C1-4 ALKYL GROUP OR THE LIKE.]