Antigen binding proteins to oncostatin m (osm)

摘要

Disclosed is an antigen binding protein which specifically binds to Oncostatin M (OSM) and which inhibits the binding of OSM to the gp130 receptor but does not directly interact with site II residues and wherein the antigen binding protein comprises the CDRs of the sequences as defined in the specification. Also disclosed is the use of the antigen binding protein in the manufacture of a medicament for treating a human patient afflicted with an inflammatory disorder or disease.