| 发明名称 |
Methods and compositions for cns delivery of heparan n-sulfatase |
| 摘要 |
<p>Disclosed is a stable formulation comprising a heparin N-sulfatase (HNS) protein at a concentration at or greater than about 5 mg/ml, and wherein the formulation comprises no greater than 50 mM of phosphate.</p> |
| 申请公布号 |
NZ605874(A) |
申请公布日期 |
2015.02.27 |
| 申请号 |
NZ20110605874 |
申请日期 |
2011.06.25 |
| 申请人 |
SHIRE HUMAN GENETIC THERAPIES INC |
发明人 |
NATOLI FARAH;TEREW JENNIFER;JIANG YUAN;TSUNG JAMIE;VERNAGLIA BRIAN;ZHU GAOZHONG;SHAHROKH ZAHRA;CALIAS PERICLES;PAN JING;PFEIFER RICHARD |
| 分类号 |
A61K38/46;A61K38/00 |
主分类号 |
A61K38/46 |
| 代理机构 |
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代理人 |
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