| 发明名称 |
COMPOUNDS CONTAINING S-N-VALERYL-N--VALINE AND (2R,4S)-5-BIPHENYL-4-YL-4-(3-CARBOXY-PROPIONYLAMINO)-2-METHYL-PENTANOIC ACID ETHYL ESTER MOIETIES AND CATIONS |
| 摘要 |
A method for treatment of a cardiovascular or renal condition or disease with a specific combination, linked pro-drug or a compound of an angiotensin receptor antagonist and a NEPi. |
| 申请公布号 |
US2015057322(A1) |
申请公布日期 |
2015.02.26 |
| 申请号 |
US201414311788 |
申请日期 |
2014.06.23 |
| 申请人 |
Feng Li;Godtfredsen Sven Erik;Sutton Paul Allen;Prashad Mahavir;Girgis Michael J.;Hu Bin;Liu Yugang;Blacklock Thomas J.;Karpinski Piotr Henryk |
发明人 |
Feng Li;Godtfredsen Sven Erik;Sutton Paul Allen;Prashad Mahavir;Girgis Michael J.;Hu Bin;Liu Yugang;Blacklock Thomas J.;Karpinski Piotr Henryk |
| 分类号 |
C07D207/50 |
主分类号 |
C07D207/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treatment of a cardiovascular or renal condition or disease in a patient in need thereof comprising administering to the patient a therapeutically effective amount of trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3′-methyl-2′-(pentanoyl{2″-(tetrazol-5-ylate)biphenyl-4′-ylmethyl}amino)butyrate] hemipentahydrate. |
| 地址 |
Pine Brook NJ US |
