发明名称 |
MULTICOMPONENT OR MONOCOMPONENT VACCINE TO BE USED AGAINST CHAGAS DISEASE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCEDURE FOR THE OBTENTION OF IMMUNOGEN OF SAID VACCINES, AND NUCLEIC ACID USED IN SAID PROCEDURE |
摘要 |
A vaccine against the Chagas disease, capable of stimulating the immune response against the trans-sialidase virulence factor of the Trypanosoma cruzi parasite, which is a multicomponent vaccine comprising: (a) an immunogenic portion formed by one or more recombinant or synthetic polypeptides or fractions of thereof and (b) one or more polynucleotides including the regions codifying one or more immunogenic polypeptides, or a monocomponent vaccine comprising at least one component selected among an immunogenic portion formed by one or more recombinant or synthetic polypeptides or fractions of them and a group of polynucleotides including the regions codifying one or more immunogenic polypeptides derived from Trypanosoma cruzi and pharmaceutical compositions containing said multicomponent and monocomponent vaccines, the procedures for obtaining the immunogen portion of said vaccines and the nucleic acid used in the procedure. |
申请公布号 |
US2015056243(A1) |
申请公布日期 |
2015.02.26 |
申请号 |
US201414529454 |
申请日期 |
2014.10.31 |
申请人 |
de Baeremaecker Barros Carlos |
发明人 |
de Baeremaecker Barros Carlos |
分类号 |
A61K39/005 |
主分类号 |
A61K39/005 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
Montevideo UY |