| 发明名称 |
PRIMING OF AN IMMUNE RESPONSE |
| 摘要 |
The present invention relates to a technology and method of priming of an immune response using invariant chain linked antigen, when these are used to prime a subsequent booster immunization using any suitable vacci. |
| 申请公布号 |
US2015056227(A1) |
申请公布日期 |
2015.02.26 |
| 申请号 |
US201414482452 |
申请日期 |
2014.09.10 |
| 申请人 |
University of Copenhagen |
发明人 |
Holst Peter Johannes;Thomsen Allen Randrup;Christensen Jan Pravsgaard;Grujic Mirjana |
| 分类号 |
A61K39/00;C12N15/85 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A nucleic acid construct comprising sequences encoding
a. at least one invariant chain or variant thereof operatively linked at the terminal part of the invariant chain or variant thereof to b. at least one antigenic protein or peptide or an antigenic fragment of said protein or peptide, wherein said invariant chain or variant thereof does not comprise the LRMK amino acid residues of the KEY region. |
| 地址 |
Copenhagen DK |
