| 发明名称 |
INHIBITION OF A lncRNA FOR TREATMENT OF MELANOMA |
| 摘要 |
The present application relates to the field of cancer, particularly the field of melanoma. It was found that a particular long non-coding RNA (lncRNA) is specifically upregulated in melanoma (but not other tumor) cells as compared to melanocytes. Inhibition of this lncRNA in melanoma cells leads to induction of apoptosis and is a novel therapeutic strategy in the treatment of melanoma. |
| 申请公布号 |
WO2015024986(A1) |
申请公布日期 |
2015.02.26 |
| 申请号 |
WO2014EP67781 |
申请日期 |
2014.08.20 |
| 申请人 |
VIB VZW;KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D;UNIVERSITEIT GENT |
发明人 |
MARINE, JEAN-CHRISTOPHE;LEUCCI, ELEONORA;VANDESOMPELE, JOKE;MESTDAGH, PIETER |
| 分类号 |
C12N15/113;A61K31/7088;A61K31/712;A61K31/713;A61P35/00;C12Q1/68;G01N33/50 |
主分类号 |
C12N15/113 |
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