发明名称 Tetrazole-substituted arylamides
摘要 Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R 1 is optionally substituted tetrazolyl, R 2 is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R 3 , R 4 , R 5 and R 6 are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X 3 and/or a P2X 2/3 receptor antagonist and methods of making the compounds.
申请公布号 IL236492(D0) 申请公布日期 2015.02.26
申请号 IL20140236492 申请日期 2014.12.28
申请人 F. HOFFMANN-LA ROCHE AG 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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