发明名称 |
PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE |
摘要 |
<p>The present invention relates to a pharmaceutical composition for the prevention and treatment of non-alcoholic fatty liver disease (NAFLD), including a conjugate prepared by covalently linking an insulinotropic peptide, a non-peptidyl polymer and an immunoglobulin Fc region. The composition of the present invention maintains the in-vivo activity of the peptide at a relatively high level, and remarkably increases the blood half-life, thereby preventing triglyceride accumulation which is a typical feature of non-alcoholic fatty liver disease. Ultimately, it can be desirably employed for the prevention and treatment of non-alcoholic fatty liver disease.</p> |
申请公布号 |
EP2838549(A1) |
申请公布日期 |
2015.02.25 |
申请号 |
EP20130757286 |
申请日期 |
2013.03.08 |
申请人 |
HANMI SCIENCE CO., LTD. |
发明人 |
LIM, SE YOUNG;PARK, SUNG HEE;SHIN, RYOUNG AE;CHOI, IN YOUNG;KWON, SE CHANG |
分类号 |
A61K38/17;A61K38/16;A61K38/26;A61K47/48;A61P1/16 |
主分类号 |
A61K38/17 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|