发明名称 |
PREPARATION AND/OR PURIFICATION OF OLIGONUCLEOTIDE CONJUGATES |
摘要 |
<p>Methods, systems and/or kits for the preparation, purification and isolation of oligonucleotide conjugates, comprising conjugation of modified antibodies or proteins with at least one modified oligonucleotide at greater than 80% efficiency to form oligonucleotide conjugates and isolating the oligonucleotide conjugates from the conjugation solution by binding the conjugates to an immobilized binder, wherein the binder may be a metal ion or an antibody.</p> |
申请公布号 |
EP2534174(A4) |
申请公布日期 |
2015.02.25 |
申请号 |
EP20110742833 |
申请日期 |
2011.02.11 |
申请人 |
SOLULINK, INC. |
发明人 |
SCHWARTZ, DAVID, A.;MENDOZA, LEOPOLDO, G. |
分类号 |
A61K47/48;C07K1/00;C07K1/22;C07K16/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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