| 摘要 |
<p>The present invention provides an avian influenza vaccine containing a peptide-bound liposome wherein;
the peptide contains:
(1) an amino acid sequence shown by any one of SEQ ID NO:1 to 9, or
(2) an amino acid sequence shown by any one of SEQ ID NO:1 to 9 wherein one or two amino acids are substituted,
has a length of 9 to 11 amino acids, and
is capable of inducing HLA-restricted cytotoxic T lymphocytes; wherein the liposome contains a phospholipid having an acyl group with 14 to 24 carbon atoms and one unsaturated bond or a hydrocarbon group with 14 to 24 carbon atoms and one unsaturated bond, and a liposome stabilizer; and
wherein the peptide is bound to the surface of the liposome.</p> |
