| 发明名称 |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof |
| 摘要 |
<p>The present invention is directed to sequence-optimized CD 123 x CD3 bi-specific monovalent diabodies that are capable of simultaneous binding to CD123 and CD3, and to the uses of such diabodies in the treatment of hematologic malignancies.</p> |
| 申请公布号 |
EP2839842(A1) |
申请公布日期 |
2015.02.25 |
| 申请号 |
EP20130198784 |
申请日期 |
2013.12.20 |
| 申请人 |
MACROGENICS, INC. |
发明人 |
BONVINI, EZIO;JOHNSON, LESLIE S.;HUANG, LING;MOORE, PAUL A.;CHICHILI, GURUNADH REDDY;ALDERSON, RALPH FROMAN |
| 分类号 |
A61K39/395;C07K16/28;C07K16/32 |
主分类号 |
A61K39/395 |
| 代理机构 |
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